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Rabbit Anti-SLC22A3/APC Conjugated antibody (bs-19807R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19807R-APC
英文名稱1 Rabbit Anti-SLC22A3/APC Conjugated antibody
中文名稱 APC標記的溶質載體家族蛋白22成員A3抗體
別    名 EMT; EMT organic cation transporter 3; EMTH; Extraneuronal monoamine transporter; OCT 3; OCT3; Orct 3; Orct3; Organic cation transporter 3; S22A3_HUMAN; SLC22 A3; SLC22A 3; Slc22a3; Solute carrier family 22 (extraneuronal monoamine transporter) member 3; Solute carrier family 22 (organic cation transporter) member 3; Solute carrier family 22 member 3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC22A3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008]

Function:
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.

Similarity:
Belongs to the major facilitator superfamily. Organic cation transporter family.

Database links:

Entrez Gene: 6581 Human

Entrez Gene: 20519 Mouse

Entrez Gene: 29504 Rat

Omim: 604842 Human

SwissProt: O75751 Human

SwissProt: Q9WTW5 Mouse

SwissProt: O88446 Rat

Unigene: 567337 Human

Unigene: 99252 Mouse

Unigene: 24231 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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