產品編號 | bs-20841R-PE-Cy5 |
英文名稱1 | Rabbit Anti-CCL27/PE-Cy5 Conjugated antibody |
中文名稱 | PE-Cy5標記的皮膚T細胞虜獲趨化因子抗體 |
別 名 | ALP; CTACK; C-C motif chemokine 27; CC chemokine ILC; Ccl27; CTAK; Cutaneous T cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL 11 R alpha locus chemokine; IL-11 R-alpha-locus chemokine; PESKY; SCYA27; Skinkine; Small inducible cytokine A27; Small-inducible cytokine A27. |
規格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 免疫學 趨化因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Mouse, Rat, ) |
產品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 19kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCL27 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq]. Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10. Subunit: Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization. Subcellular Location: Secreted. Tissue Specificity: Testis, thymus, placenta, ovary and skin. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 100039863 Mouse Entrez Gene: 100039939 Mouse Entrez Gene: 100040048 Mouse Entrez Gene: 20301 Mouse SwissProt: Q9Z1X0 Mouse Unigene: 335946 Mouse Unigene: 425176 Mouse Unigene: 484274 Mouse Unigene: 6660 Mouse Unigene: 78371 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CCL27是一種CC型趨化因子,又被稱為Skinkine,ESkine和CTACK。CCL27基因位于人類染色體9,它與皮膚上歸巢的記憶T淋巴細胞有關,并在T細胞介導的皮膚炎癥中起著重要的作用。CCL27表達在許多組織,包括性腺,胸腺,胎盤和皮膚。其配體為CCR10,CCL27與接觸性軟疣病毒編碼產生的蛋白質MC148有較高的同源性,但卻與人皰疹病毒8型編碼產生病毒巨噬細胞炎癥蛋白-Ⅱ競爭結合受體CCR10。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |