產(chǎn)品編號(hào) | bs-18821R-BF555 |
英文名稱1 | Rabbit Anti-MEX3C/BF555 Conjugated antibody |
中文名稱 | BF555標(biāo)記的MEX3C蛋白抗體 |
別 名 | BM 013; BM013; FLJ38871; Mex 3 homolog C C. elegans; Mex 3, C. elegans, homolog of C; MEX 3C; MEX3C; MEX3C_HUMAN; Ring finger and KH domain containing 2; RING finger and KH domain containing protein 2; RING finger and KH domain-containing protein 2; RING finger protein 194; RKHD2; RNA-binding E3 ubiquitin-protein ligase MEX3C; RNA-binding protein MEX3C; RNF194. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 結(jié)合蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 69kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MEX3C |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009] Function: RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms. Subunit: Interacts with USP7, which antagonizes the ability to degrade mRNA. Subcellular Location: Cytoplasm. Nucleus. Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Tissue Specificity: Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Week expression in the intestine. DISEASE: Note=Genetic variations in MEX3C may be associated with susceptibility to essential hypertension. Similarity: Contains 2 KH domains. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 51320 Human Entrez Gene: 240396 Mouse Omim: 611005 Human SwissProt: Q5U5Q3 Human SwissProt: Q05A36 Mouse Unigene: 465144 Human Unigene: 24131 Mouse Unigene: 436942 Mouse Unigene: 8138 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |