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Rabbit Anti-IMMP2L/BF555 Conjugated antibody (bs-16620R-BF555)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-16620R-BF555
英文名稱(chēng)1 Rabbit Anti-IMMP2L/BF555 Conjugated antibody
中文名稱(chēng) BF555標(biāo)記的線(xiàn)粒體內(nèi)膜蛋白酶樣IMP2抗體
別    名 EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; IMP2L_HUMAN; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IMMP2L
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]

Function:
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMMPL1 and IMMPL2 are the catalytic subunits of the IMP complex.

Subunit:
Heterodimer of 2 subunits, IMMPL1 and IMMPL2 (By similarity).

Subcellular Location:
Mitochondrion inner membrane; Single pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested except adult liver and lung.

DISEASE:
Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the peptidase S26 family. IMP2 subfamily.

Database links:

Entrez Gene: 83943 Human

Omim: 605977 Human

SwissProt: Q96T52 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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