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Rabbit Anti-SGLT2/PE Conjugated antibody (bs-20084R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-20084R-PE
英文名稱1 Rabbit Anti-SGLT2/PE Conjugated antibody
中文名稱 PE標(biāo)記的鈉/葡萄糖協(xié)同轉(zhuǎn)運蛋白2抗體
別    名 Low affinity sodium glucose cotransporter; Low affinity sodium-glucose cotransporter; Na(+) glucose cotransporter 2; Na(+)/glucose cotransporter 2; OTTHUMP00000163298; SC5A2_HUMAN; SGLT 2; SLC5A 2; SLC5A2; Sodium glucose cotransporter 2; Sodium/glucose cotransporter 2; Solute carrier family 5 (sodium glucose cotransporter) member 2; Solute carrier family 5 (sodium/glucose transporter), member 2; Solute carrier family 5 member 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SGLT2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]

Function:
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

Subcellular Location:
Membrane.

DISEASE:
Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.

Similarity:
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Database links:

Entrez Gene: 6524 Human

Entrez Gene: 399680 Cow

Entrez Gene: 492301 Dog

Entrez Gene: 246787 Mouse

Entrez Gene: 64522 Rat

Omim: 182381 Human

SwissProt: P31639 Human

SwissProt: Q923I7 Mouse

SwissProt: P26430 Rabbit

SwissProt: P53792 Rat

Unigene: 709195 Human

Unigene: 38870 Mouse

Unigene: 5887 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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