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Rabbit Anti-GABA Transporter 3/Cy5 Conjugated antibody (bs-13260R-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13260R-Cy5
英文名稱1 Rabbit Anti-GABA Transporter 3/Cy5 Conjugated antibody
中文名稱 Cy5標記的γ氨基丁酸運載蛋白3抗體
別    名 GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium- and chloride-dependent GABA transporter 3; SOLUTE CARRIER FAMILY 6 (NEUROTRANSMITTER TRANSPORTER, GABA), MEMBER 11; Solute carrier family 6 member 11.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABA Transporter 3/GAT 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010]

Function:
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Widespread distribution in the brain.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.

Database links:

Entrez Gene: 6538 Human

Omim: 607952 Human

SwissProt: P48066 Human

Unigene: 657405 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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