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Rabbit Anti-Nidogen2/RBITC Conjugated antibody (bs-10075R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10075R-RBITC
英文名稱1 Rabbit Anti-Nidogen2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的骨巢蛋白抗體
別    名 NID 2; NID2; Nidogen2; Nidogen 2; Nidogen-2; Osteonidogen; NID2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  細胞周期蛋白  細胞粘附分子  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 148kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nidogen2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Nidogen 2 is an adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell extracellular matrix interactions.

Function:
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.

Subunit:
Interacts with LAMA2. Interacts with COL13A1.

Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane.

Tissue Specificity:
Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.

Post-translational modifications:
Highly N- and O-glycosylated.

Similarity:
Contains 5 EGF-like domains.
Contains 5 LDL-receptor class B repeats.
Contains 1 NIDO domain.
Contains 1 nidogen G2 beta-barrel domain.
Contains 2 thyroglobulin type-1 domains.

Database links:

Entrez Gene: 22795 Human

Entrez Gene: 18074 Mouse

Omim: 605399 Human

SwissProt: Q14112 Human

SwissProt: O88322 Mouse

Unigene: 147697 Human

Unigene: 369840 Human

Unigene: 20348 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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