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Rabbit Anti-RTF1/RBITC Conjugated antibody (bs-12261R-RBITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12261R-RBITC
英文名稱1 Rabbit Anti-RTF1/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的組織相容性復合物RTF1抗體
別    名 CDG1N; GTL 7; GTL7; KIAA0252; Ortholog of mouse gene trap locus 7; RNA polymerase associated protein RTF1 homolog; RNA polymerase-associated protein RTF1 homolog; RTF 1; RTF1; Rtf1 Paf1/RNA polymerase II complex component homolog; RTF1_HUMAN; rtf1L; YGL244W;  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 干細胞  內皮細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human RTF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus.

Function:
Plays a role in transcription-coupled histone modification. Plays a role in regulation of transcription. Required for maximal induction of heat-shock genes (By similarity). Binds single-stranded DNA.

Subunit:
Component of the PAF1 complex, which consists of CDC73, PAF1, LEO1, CTR9, RTF1 and WDR61; the association of RTF1 appears to be less stable than that of other subunits. At least in HeLa cells a N-terminal shorter form of RTF1 is also found in the complex.

Subcellular Location:
Nucleus, nucleoplasm (By similarity).

Similarity:
Contains 1 Plus3 domain.

Database links:
UniProtKB/Swiss-Prot: Q92541.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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