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Rabbit Anti-MMP-23/FITC Conjugated antibody (bs-5875R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5875R-FITC
英文名稱1 Rabbit Anti-MMP-23/FITC Conjugated antibody
中文名稱 FITC標記的基質金屬蛋白酶23抗體
別    名 Cysteine array matrix metalloproteinase; Femalysin; Matrix metallopeptidase 21; Matrix metallopeptidase 23A (pseudogene); Matrix metallopeptidase 23A; Matrix metallopeptidase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase 23; Matrix metalloproteinase 23B; Matrix metalloproteinase in the female reproductive tract; Matrix metalloproteinase-21; Matrix metalloproteinase-22; Matrix metalloproteinase-23; MIFR 1; MIFR; MIFR-1; MIFR1; MMP 21; MMP 22; MMP 23; MMP 23B; MMP-21; MMP-22; MMP-23; MMP21; MMP22; MMP23_HUMAN; MMP23A; MMP23B; soluble form;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  激酶和磷酸酶  細胞骨架  細胞外基質  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36/44kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MMP-23
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Matrix Metalloproteinase 23 is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.

Function:
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity). Membrane; Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist (Probable).

Tissue Specificity:
Predominantly expressed in ovary, testis and prostate.

Post-translational modifications:
N-glycosylated.
Proteolytic cleavage might yield an active form (By similarity).

Similarity:
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 8510 Human

Entrez Gene: 26561 Mouse

Entrez Gene: 94339 Rat

Omim: 603321 Human

SwissProt: O75900 Human

SwissProt: O88676 Mouse

SwissProt: O88272 Rat

Unigene: 192316 Human

Unigene: 671760 Human

Unigene: 29373 Mouse

Unigene: 22562 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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