產(chǎn)品編號 | bs-5151R-Gold |
英文名稱1 | Rabbit Anti-Acrosin/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的精子頂體前體蛋白抗體 |
別 名 | ACR; Acrosin precursor; ACRS;Preproacrosin; Proacrosin; ACRO_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 33/44kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Acrosin heavy chain |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. Function: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. Subunit: Heavy chain (catalytic) and a light chain linked by two disulfide bonds. Forms heterodimer with SERPINA5. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Database links: Entrez Gene: 49 Human Omim: 102480 Human SwissProt: P10323 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |