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Rabbit Anti-FBXL17/AP Conjugated antibody (bs-8469R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8469R-AP
英文名稱1 Rabbit Anti-FBXL17/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的FBXL17蛋白抗體
別    名 F box and leucine rich repeat protein 17; F box only protein 13; F box/LRR repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17; FBL17; FBX13; Fbxl17; FBXO13; FBXL13; FXL17_HUMAN; DKFZP434C1715.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXL17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Interacts with SKP1 and CUL1

Similarity:
Contains 1 F-box domain.

Database links:

Entrez Gene: 64839 Human

Entrez Gene: 50758 Mouse

Entrez Gene: 316663 Rat

Omim: 609083 Human

SwissProt: Q9UF56 Human

SwissProt: Q9QZN1 Mouse

Unigene: 657225 Human

Unigene: 721914 Human

Unigene: 136366 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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