產(chǎn)品編號 | bs-2463R-AP |
英文名稱1 | Rabbit Anti-TNFSF4/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的腫瘤壞死因子配體超家族成員4抗體 |
別 名 | CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞表面分子 淋巴細(xì)胞 t-淋巴細(xì)胞 細(xì)胞因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from rat TNFSF4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq] Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. Subunit: Homotrimer (Probable). Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Detected in T-cell lines, but not in a macrophage cell line. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 7292 Human Entrez Gene: 22164 Mouse Omim: 603594 Human SwissProt: P23510 Human SwissProt: P43488 Mouse Unigene: 181097 Human Unigene: 4994 Mouse Unigene: 30043 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |