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Rabbit Anti-EGFL7/BF647 Conjugated antibody (bs-1755R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1755R-BF647
英文名稱1 Rabbit Anti-EGFL7/BF647 Conjugated antibody
中文名稱 BF647標記的類表皮生長因子域7抗體
別    名 EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGFL 7; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple epidermal growth factor like domain protein 7; NEU1 protein; NOTCH4 like protein; RP11 251M1.2; Vascular endothelial statin; VE statin; ZNEU 1; ZNEU1; EGFL7_HUMAN; EGFL7_MOUSE.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  生長因子和激素  轉錄調節因子  激酶和磷酸酶  內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse EGFL7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Function:
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Subcellular Location:
Secreted (By similarity).

Tissue Specificity:
Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney.

Similarity:
Contains 2 EGF-like domains.
Contains 1 EMI domain.

Database links:

Entrez Gene: 51162 Human

Entrez Gene: 353156 Mouse

Omim: 608582 Human

SwissProt: Q9UHF1 Human

Unigene: 91481 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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