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Rabbit Anti-CD161c/FITC Conjugated antibody (bs-4682R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4682R-FITC
英文名稱1 Rabbit Anti-CD161c/FITC Conjugated antibody
中文名稱 FITC標記的CD161c抗體
別    名 CD161 antigen like family member C; CD161 antigen-like family member C; CD161c; Killer cell lectin like receptor subfamily A member 1C; Killer cell lectin like receptor subfamily B member 1C; Klrb1c; Ly55c; Lymphocyte antigen 55c; Ly59; Lymphocyte antigen 59; Natural killer cell surface protein P1 40; Natural killer cell surface protein P1-40; Ly-55c; NK1.1 alloantigen; NKR P1.9; NKR P1C; NKRP1 40; NKRP1; NKRP1.9; Nkrp1-c; NKRP1C; NK-1.1; Nk-1.2; NK-RP1; NK1.1; NKR-P1; Nkrp1c; NKR-P1.9; NKR-P1C; KLRB1_MOUSE.  
Journal
PMID
IF
Application
[IF=8.402] Zhang Y et al. Recombinant adenovirus expressing a soluble fusion protein PD-1/CD137L subverts the suppression of CD8+ T cells in hepatocellular carcinoma. Mol Ther. 2019 Aug 5. pii: S1525-0016(19)30358-2.  FCM ;  Mouse&Human.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  信號轉導  細胞膜受體  自然殺傷細胞  t-淋巴細胞  上皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CD161/NK1.1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
NK1.1, a member of the NKRPI family of cell surface receptors, is a type II integral membrane protein with a C type lectin domain. It is expressed as a disulfide linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells.

Subunit:
Homodimer; disulfide-linked. Interacts with acid phingomyelinase/SMPD1.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Tissue Specificity:
Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 3820 Human

Entrez Gene: 100043861 Mouse

Entrez Gene: 362443 Rat

Omim: 602890 Human

SwissProt: Q12918 Human

SwissProt: Q0ZUP1 Mouse

SwissProt: Q0ZUP0 Rat

Unigene: 169824 Human

Unigene: 66911 Mouse

Unigene: 198693 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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