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Rabbit Anti-GRP75/Gold Conjugated antibody (bs-1469R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-1469R-Gold
英文名稱1 Rabbit Anti-GRP75/Gold Conjugated antibody
中文名稱 膠體金標記的G蛋白偶聯受體75抗體
別    名 G protein-coupled receptor75; 75 kDa glucose regulated protein; 75 kDa glucose-regulated protein; CSA; Glucose Regulated Protein; Grp 75; GRP75; Heat shock 70kD protein 9; heat shock 70kDa protein 9; Heat shock 70kDa protein 9B; Heat shock protein 74 kDa A; Heat shock protein A; Heat shock protein cognate 74; Hsc74; Hsp74; Hsp74a; HSPA9; Hspa9a; HSPA9B; MGC4500; Mortalin 2; Mortalin; Mortalin perinuclear; Mortalin2; MOT 2; MOT; MOT2; Mthsp70; p66 mortalin; P66 MOT; PBP74; Peptide binding protein 74; Stress 70 protein mitochondrial; Stress 70 protein mitochondrial precursor.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  免疫學  信號轉導  細胞膜受體  轉運蛋白  G蛋白偶聯受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GRP75
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.

Function:
Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.

Subunit:
Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2.

Subcellular Location:
Mitochondrion. Nucleus, nucleolus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the heat shock protein 70 family.

Database links:

Entrez Gene: 3313 Human

Entrez Gene: 15526 Mouse

Entrez Gene: 291671 Rat

Omim: 600548 Human

SwissProt: P38646 Human

SwissProt: P38647 Mouse

SwissProt: P48721 Rat

Unigene: 184233 Human

Unigene: 209419 Mouse

Unigene: 7535 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

信號傳導(Signaling Intermediates)
葡萄糖調節蛋白75
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