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Rabbit Anti-CXCR5  antibody (bsm-54319R)  
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產(chǎn)品編號 bsm-54319R
英文名稱 Rabbit Anti-CXCR5  antibody
中文名稱 細胞表面趨化因子受體5(CD185)重組兔單抗
別    名 BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15.  
Specific References  (1)     |     bsm-54319R has been referenced in 1 publications.
[IF=5.736] Maria Chiara Trolese. et al. CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis. Ebiomedicine. 2020 Dec;62:103097  IHC ;  Mouse.  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  趨化因子  G蛋白偶聯(lián)受體  b-淋巴細胞  G蛋白信號  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 3B7
交叉反應 Human,Mouse,Rat
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human CXCR5 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Function:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expression in mature B-cells and Burkitt lymphoma cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P32302

Gene ID:
643

Database links:

Entrez Gene: 643 Human

Entrez Gene: 12145 Mouse

Entrez Gene: 29363 Rat

Omim: 601613 Human

SwissProt: P32302 Human

SwissProt: Q04683 Mouse

SwissProt: P34997 Rat

Unigene: 113916 Human

Unigene: 490637 Mouse

Unigene: 6246 Mouse

Unigene: 120732 Rat

Unigene: 127121 Rat



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with CXCR5 monoclonal antibody, unconjugated (bsm-54319R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded Human Lymph; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Mouse Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Rat Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CXCR5 Monoclonal Antibody, Unconjugated(bsm-54319R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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