国产亚洲欧美二区,欧美巨大另类极品videosbest,久久国产精品偷,超刺激h直播间play

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  人才招聘  關于我們  聯系我們
色窝窝无码一区二区三区成人网站,天天干天天射天天操,久久久国产精品福利片
首頁 > 產品中心 > 一抗 > 產品信息
Mouse Anti-Human VEGF165  antibody (bsm-41663M)  
訂購熱線:400-901-9800
訂購郵箱:sales@ythxkj.com
訂購QQ:  400-901-9800
技術支持:techsupport@ythxkj.com
說明書: 100ug  
100ug/2500.00元
200ug(PBS only)/5600.00元
大包裝/詢價

產品編號 bsm-41663M
英文名稱 Mouse Anti-Human VEGF165  antibody
中文名稱 人血管內皮生長因子單克隆抗體
別    名 VEGF165; Vascuoar endothelial growth factor A; VEGF A; vascular endothelial growth factor A isoform 2 precursor; Vegf; VEGFA; MGC70609; MVCD1; VEGF; VPF; VEGFA_HUMAN; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGF A Precursor.  
研究領域 心血管  生長因子和激素  血管內皮細胞  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 19D2
交叉反應 Human
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 18kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
免 疫 原 Recombinant human VEGF165 Protein: 27-191/191 
亞    型 IgG2b
純化方法 affinity purified by Protein A
緩 沖 液 0.01M PBS (pH7.4).
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature).

Function:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Subunit:
Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity).

Subcellular Location:
Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin. Tissue Specificity : Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed.

DISEASE:
Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1) [MIM:603933]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.

Similarity:
Belongs to the PDGF/VEGF growth factor family.

SWISS:
P15692

Gene ID:
7422

Database links:

Entrez Gene: 7422 Human

Entrez Gene: 22339 Mouse

Entrez Gene: 83785 Rat

Omim: 192240 Human

SwissProt: P15692 Human

SwissProt: Q00731 Mouse

SwissProt: P16612 Rat

Unigene: 73793 Human

Unigene: 282184 Mouse

Unigene: 1923 Rat



產品圖片
Sample: Lane 1: Recombinant Human VEGF165 Protein at 500ng Primary: Mouse Anti-VEGF165 Monoclonal Antibody at 1/1000 dilution (Cat.bsm-41663M) Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 21kD Observed band size: 25kD
Measured by its binding ability in a indirect ELISA. Immobilized Human VEGF165, His Tag (Cat. bs-41613P) at 2 μg/mL (100 μL/well) can bind Anti-Human VEGF165 monoclonal antibody, the minimum detection concentration is 2ng/mL
版權所有 2004-2026 www.ythxkj.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號