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Mouse Anti-MX1  antibody (bsm-51528M)  
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產品編號 bsm-51528M
英文名稱 Mouse Anti-MX1  antibody
中文名稱 MX1單克隆抗體
別    名 N-terminally processed; Human interferon regulated resistance GTP binding protein MXA; IFI 78; IFI 78K; IFI-78K; IFI78; IFI78K; Interferon induced GTP binding protein Mx1; Interferon induced protein p78; Interferon inducible protein p78; Interferon regulated resistance GTP binding protein; Interferon regulated resistance GTP binding protein MxA; Interferon-induced GTP-binding protein Mx1; Interferon-induced protein p78; Interferon-regulated resistance GTP-binding protein MxA; MX 1; MX; MX1; MX1_HUMAN; MxA; Myxoma resistance protein 1; Myxovirus (influenza virus) resistance 1 interferon inducible; Myxovirus (influenza virus) resistance 1 interferon inducible protein p78; Myxovirus (influenza) resistance 1 homolog of murine; Myxovirus resistance protein 1.  
研究領域 心血管  細胞生物  合成與降解  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 C3G6
交叉反應 Human (predicted: Pig)
產品應用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 73kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MX1: 601-662/662 
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function:
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus.

Subunit:
Homotetramer.

Subcellular Location:
Secreted, extracellular space. Nucleus. Note=Translocates into the nuclei of HSV-1 infected cells.

Similarity:
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

SWISS:
P20591

Gene ID:
4599

Database links:

Entrez Gene: 4599 Human

SwissProt: P20591 Human



產品圖片
Sample: Lane 1: T47D cell lysates Primary: Anti-MX1 (bsm-51528M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 73 kD Observed band size: 73 kD
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