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Rabbit Anti-EGFL7  antibody (bs-21459R)  
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產品編號 bs-21459R
英文名稱 Rabbit Anti-EGFL7  antibody
中文名稱 類表皮生長因子域7抗體
別    名 EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGFL 7; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple epidermal growth factor like domain protein 7; NEU1 protein; NOTCH4 like protein; RP11 251M1.2; Vascular endothelial statin; VE statin; ZNEU 1; ZNEU1; EGFL7_HUMAN; EGFL7_MOUSE.  
研究領域 腫瘤  細胞生物  免疫學  生長因子和激素  激酶和磷酸酶  內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse EGFL7 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Function:
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Subcellular Location:
Secreted (By similarity).

Tissue Specificity:
Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney.

Similarity:
Contains 2 EGF-like domains.
Contains 1 EMI domain.

SWISS:
Q9QXT5

Gene ID:
353156

Database links:

Entrez Gene: 51162 Human

Entrez Gene: 353156 Mouse

Omim: 608582 Human

SwissProt: Q9UHF1 Human

Unigene: 91481 Human



產品圖片
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- EGFL7 (bs-21459R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 25 kD
Sample: 293T(Human) Cell Lysate at 30 ug Primary: Anti- EGFL7 (bs-21459R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD
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