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Rabbit Anti-VPS37C  antibody (bs-12774R)  
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產品編號 bs-12774R
英文名稱 Rabbit Anti-VPS37C  antibody
中文名稱 液泡蛋白分選蛋白37C抗體
別    名 5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; FLJ20847; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37 homolog C (S. cerevisiae); Vacuolar protein sorting 37C (yeast); Vacuolar protein sorting 37C; Vacuolar protein sorting associated protein 37C; Vacuolar protein sorting-associated protein 37C; VP37C_HUMAN; VPS37C.  
研究領域 細胞生物  信號轉導  跨膜蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS37C: 11-110/355 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

Subcellular Location:
Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.

Similarity:
Belongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain.

SWISS:
A5D8V6

Gene ID:
55048

Database links:

Entrez Gene: 55048 Human

Entrez Gene: 107305 Mouse

Entrez Gene: 308178 Rat

Omim: 610038 Human

SwissProt: A5D8V6 Human

SwissProt: Q8R105 Mouse

Unigene: 523715 Human

Unigene: 19091 Mouse

Unigene: 12915 Rat



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