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Rabbit Anti-TMPRSS11D  antibody (bs-12672R)  
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產品編號 bs-12672R
英文名稱 Rabbit Anti-TMPRSS11D  antibody
中文名稱 跨膜絲氨酸蛋白酶11D抗體
別    名 Airway trypsin like protease; Airway trypsin-like protease; HAT; MGC150587; MGC150588; TM11D_HUMAN; TMPRSS11D; Transmembrane protease serine 11D; Transmembrane protease serine 11D catalytic chain; Transmembrane protease serine 11D precursor.  
研究領域 細胞生物  跨膜蛋白  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46kDa
細胞定位 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMPRSS11D: 21-120/418 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]

Function:
May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Subcellular Location:
Secreted. Activated by cleavage and secreted and Cell membrane. Activated by cleavage and secreted.

Tissue Specificity:
Located in the cells of the submucosal serous glands of the bronchi and trachea.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain.

SWISS:
O60235

Gene ID:
9407

Database links:

Entrez Gene: 9407 Human

Omim: 605369 Human

SwissProt: O60235 Human

Unigene: 132195 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TM11D) Polyclonal Antibody, Unconjugated (bs-12672R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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