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Rabbit Anti-SerpinB8  antibody (bs-19660R)  
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產品編號 bs-19660R
英文名稱 Rabbit Anti-SerpinB8  antibody
中文名稱 絲氨酸蛋白酶抑制劑B8抗體
別    名 CAP 2; CAP-2; CAP2; Cytoplasmic antiproteinase 2; OTTHUMP00000067000; OTTHUMP00000067001; Peptidase inhibitor 8; PI 8; PI-8; PI8; Protease inhibitor 8 (ovalbumin type); Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8; Serpin B8; Serpin peptidase inhibitor clade B (ovalbumin) member 8; Serpinb8; SPB8_HUMAN.  
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,Cat,GuineaPig,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 43kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SerpinB8: 121-220/374 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).[supplied by OMIM, Jan 2010]

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

SWISS:
P50452

Gene ID:
5271

Database links:

Entrez Gene: 5271 Human

Entrez Gene: 20725 Mouse

Entrez Gene: 288937 Rat

Omim: 601697 Human

SwissProt: P50452 Human

SwissProt: O08800 Mouse

Unigene: 368077 Human

Unigene: 83909 Mouse

Unigene: 104823 Rat



產品圖片
Sample: SW480(human) Cell Lysate at 40 ug Primary: Anti-SerpinB8 (bs-19660R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD
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