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Rabbit Anti-TRIM29 (acetyl K116)  antibody (bs-16731R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-16731R
英文名稱 Rabbit Anti-TRIM29 (acetyl K116)  antibody
中文名稱 乙酰化TRIM29蛋白抗體
別    名 Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29.  
產品類型 乙酰化抗體 
研究領域 細胞生物  免疫學  信號轉導  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Rabbit,Pig,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 66kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116: AK(Ac-K)PP 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]

Function:
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.

Subcellular Location:
Cytoplasm. Colocalizes with intermediate filaments.

Tissue Specificity:
Expressed in placenta, prostate and thymus.

Post-translational modifications:
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.

Similarity:
Contains 1 B box-type zinc finger.

SWISS:
Q14134

Gene ID:
23650

Database links:

Entrez Gene: 23650 Human

Entrez Gene: 525062 Cow

Entrez Gene: 72169 Mouse

Entrez Gene: 300656 Rat

Omim: 610658 Human

SwissProt: Q14134 Human

SwissProt: Q8R2Q0 Mouse

Unigene: 504115 Human

Unigene: 273277 Mouse



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