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Rabbit Anti-IMMP2L  antibody (bs-16620R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-16620R
英文名稱 Rabbit Anti-IMMP2L  antibody
中文名稱 線粒體內膜蛋白酶樣IMP2抗體
別    名 EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; IMP2L_HUMAN; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189.  
研究領域 腫瘤  細胞生物  信號轉導  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IMMP2L: 31-130/175 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]

Function:
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMMPL1 and IMMPL2 are the catalytic subunits of the IMP complex.

Subunit:
Heterodimer of 2 subunits, IMMPL1 and IMMPL2 (By similarity).

Subcellular Location:
Mitochondrion inner membrane; Single pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested except adult liver and lung.

DISEASE:
Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the peptidase S26 family. IMP2 subfamily.

SWISS:
Q96T52

Gene ID:
83943

Database links:

Entrez Gene: 83943 Human

Omim: 605977 Human

SwissProt: Q96T52 Human



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