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Rabbit Anti-FXL19  antibody (bs-16201R)  
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產品編號 bs-16201R
英文名稱 Rabbit Anti-FXL19  antibody
中文名稱 FXL19蛋白抗體
別    名 F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C.  
研究領域 細胞生物  跨膜蛋白  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FXL19: 401-500/694 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Directly interacts with SKP1 and CUL1 (By similarity).

Similarity:
Contains 1 CXXC-type zinc finger.
Contains 1 F-box domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 PHD-type zinc finger.

SWISS:
Q6PCT2

Gene ID:
54620

Database links:

Entrez Gene: 54620 Human

Entrez Gene: 233902 Mouse

Entrez Gene: 308999 Rat

GenBank: BC059173 Human

Omim: 609085 Human

SwissProt: Q6PCT2 Human

SwissProt: Q6PB97 Mouse

Unigene: 152149 Human



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