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Rabbit Anti-FBXO8  antibody (bs-16053R)  
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產(chǎn)品編號(hào) bs-16053R
英文名稱(chēng) Rabbit Anti-FBXO8  antibody
中文名稱(chēng) FBXO8蛋白抗體
別    名 DC10; F box only protein 8; F box protein 8; F box protein Fbx8; F box/SEC7 protein FBS; F-box only protein 8; F-box/SEC7 protein FBS; FBS; FBX8; FBX8_HUMAN; FBXO 8; Fbxo8.  
研究領(lǐng)域 細(xì)胞生物  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO8: 221-319/319 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]

Function:
May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP.

Similarity:
Contains 1 F-box domain.
Contains 1 SEC7 domain.

SWISS:
Q9NRD0

Gene ID:
26269

Database links:

Entrez Gene: 26269 Human

Entrez Gene: 50753 Mouse

Entrez Gene: 306436 Rat

Omim: 605649 Human

SwissProt: Q5E9G6 Cow

SwissProt: Q9NRD0 Human

SwissProt: Q9QZN3 Mouse

Unigene: 76917 Human

Unigene: 251174 Mouse

Unigene: 91689 Rat



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