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Rabbit Anti-DPEP1  antibody (bs-14414R)  
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產品編號 bs-14414R
英文名稱 Rabbit Anti-DPEP1  antibody
中文名稱 脫氫肽酶1抗體
別    名 Dehydropeptidase-I; Dipeptidase 1 (renal); Dipeptidase 1; DPEP1; DPEP1_HUMAN; hRDP; MBD1; MDP; Microsomal dipeptidase; RDP; Renal dipeptidase.  
研究領域 腫瘤  心血管  細胞生物  神經生物學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 44kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPEP1: 201-300/411 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.

Subcellular Location:
Apical cell membrane. Cell projection; microvillus membrane. Brush border membrane.

Similarity:
Belongs to the peptidase M19 family.

SWISS:
P16444

Gene ID:
1800

Database links:

Entrez Gene: 1800 Human

Omim: 179780 Human

SwissProt: P16444 Human

Unigene: 109 Human



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