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Rabbit Anti-DDX46  antibody (bs-14228R)  
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產品編號 bs-14228R
英文名稱 Rabbit Anti-DDX46  antibody
中文名稱 ATP依賴RNA解旋酶DDX46抗體
別    名 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; Probable ATP dependent RNA helicase DDX46; PRP5 homolog; DDX46_HUMAN; Prp5 like DEAD-box protein; PRPF5; RNA helicase.  
研究領域 細胞生物  結合蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 117kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX46: 251-350/1031 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]

Function:
Plays an essential role in splicing, either prior to, or during splicing A complex formation.

Subcellular Location:
Nucleus speckle. Nucleus, Cajal body.

SWISS:
Q7L014

Gene ID:
9879

Database links:

Entrez Gene: 9879 Human

Entrez Gene: 212880 Mouse

Entrez Gene: 245957 Rat

SwissProt: Q7L014 Human

SwissProt: Q569Z5 Mouse

SwissProt: Q62780 Rat

Unigene: 406549 Human

Unigene: 202725 Mouse

Unigene: 3436 Rat



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