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Rabbit Anti-valyl tRNA  antibody (bs-10504R)  
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產品編號 bs-10504R
英文名稱 Rabbit Anti-valyl tRNA  antibody
中文名稱 纈氨酰-tRNA合成酶抗體
別    名 SYVM_HUMAN; Valine--tRNA ligase, mitochondrial; Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like; valyl tRNA; VARS2; KIAA1885; VARS2L; VARSL.  
研究領域 細胞生物  免疫學  合成與降解  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 115kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human vars2 : 1-100/1063 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 ValRS (valyl-tRNA synthetase), also known as Protein G7a, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ValRS joins Val to tRNA(Val) at its synthetic active site. At its CP1 editing active site, ValRS hydrolyzes or deacylates tRNA(Thr) that is incorrectly joined to Val. ValRS forms aggregates with EF-1 (elongation factor 1) and, via this complex, catalyzes the aminoacylation of tRNA and its transfer to EF-1. In addition, ValRS may be regulated by PKC-dependent phosphorylation.

Subcellular Location:
Mitochondrion (Potential).

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

SWISS:
P26640

Gene ID:
7407

Database links:

Entrez Gene: 7407 Human

Entrez Gene: 25009 Rat

Omim: 192150 Human

SwissProt: P26640 Human

SwissProt: Q04462 Rat

Unigene: 520026 Human

Unigene: 12314 Rat



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