產(chǎn)品編號(hào) | bs-15501R |
英文名稱 | Rabbit Anti-PCSK4 antibody |
中文名稱 | 原蛋白轉(zhuǎn)化酶4抗體 |
別 名 | PC4; PCSK4; PCSK4_HUMAN; Proprotein convertase 4; Proprotein convertase PC4; Proprotein convertase subtilisin/kexin type 4. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 泛素 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Cow) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 70kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PCSK4: 221-320/755 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
PCSK4 is a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II. Function: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Tissue Specificity: Placenta. Similarity: Belongs to the peptidase S8 family. Furin subfamily. Contains 1 FU (furin-like) repeat. SWISS: Q6UW60 Gene ID: 54760 Database links: Entrez Gene: 54760 Human Omim: 600487 Human SwissProt: Q6UW60 Human Unigene: 46884 Human |
產(chǎn)品圖片 | |