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Rabbit Anti-HSJ1  antibody (bs-7233R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號(hào) bs-7233R
英文名稱 Rabbit Anti-HSJ1  antibody
中文名稱 熱休克蛋白J1抗體
別    名 Descriptions; DnaJ (Hsp40) homolog subfamily B member 2; DnaJ homolog subfamily B member 2; DnaJ protein homolog 1; DNAJB2; Heat shock 40 kDa protein 3; Heat shock protein J1; Heat shock protein neuronal DNAJ like 1; HSJ 1; HSJ1; HSPF3; DNJB2_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 36kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSJ1/DNAJB2: 21-120/324 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

Tissue Specificity:
Brain (neuronal layers). Weakly, in skeletal muscle and spleen.

Similarity:
Contains 1 J domain.
Contains 2 UIM (ubiquitin-interacting motif) repeats.

SWISS:
P25686

Gene ID:
3300

Database links:

Entrez Gene: 533668 Cow

Entrez Gene: 3300 Human

Entrez Gene: 56812 Mouse

Entrez Gene: 689593 Rat

Omim: 604139 Human

SwissProt: P25686 Human

SwissProt: Q9QYI5 Mouse

Unigene: 77768 Human

Unigene: 40780 Rat



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