產(chǎn)品編號(hào) | bs-12381R |
英文名稱 | Rabbit Anti-CAMSAP1 antibody |
中文名稱 | 鈣調(diào)素調(diào)節(jié)蛋白相關(guān)蛋白抗體 |
別 名 | calmodulin regulated spectrin-associated protein 1; Calmodulin-regulated spectrin-associated protein 1; CAMP1_HUMAN; camsap1; PRO2405. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 跨膜蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 178kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CAMSAP1: 1401-1500/1602 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
CAMSAP1L1 is a 1,489 amino acid protein that contains one calponin-homology domain and one CKK domain, which serves to bind microtubules. There are three isoforms of CAMSAP1L1 that are produced as a result of alternative splicing events. The gene encoding CAMSAP1L1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the CAMSAP1 family. Contains 1 CH (calponin-homology) domain. Contains 1 CKK domain. SWISS: Q5T5Y3 Gene ID: 157922 Database links: Entrez Gene: 157922 Human Entrez Gene: 227634 Mouse SwissProt: Q5T5Y3 Human SwissProt: A2AHC3 Mouse Unigene: 522493 Human Unigene: 36834 Mouse |