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Rabbit Anti-TACI  antibody (bs-4841R)  
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產(chǎn)品編號 bs-4841R
英文名稱 Rabbit Anti-TACI  antibody
中文名稱 腫瘤壞死因子受體超家族成員13B抗體
別    名 TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B;TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B.   
研究領域 細胞生物  免疫學  淋巴細胞  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFRSF13B/CD267/TACI : 21-120/293 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

Subcellular Location:
Membrane; Single-pass type III membrane protein.

Tissue Specificity:
Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.

Similarity:
Contains 2 TNFR-Cys repeats.

SWISS:
O14836

Gene ID:
23495

Database links:

Entrez Gene: 23495 Human

Entrez Gene: 57916 Mouse

Omim: 604907 Human

SwissProt: O14836 Human

SwissProt: Q9ET35 Mouse

Unigene: 158341 Human

Unigene: 265915 Mouse



產(chǎn)品圖片
Sample: Lane 1: Mouse Stomach tissue lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-TACI (bs-4841R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 30 kDa
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti- TACI (bs-4841R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kD Observed band size: 30 kD
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