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Rabbit Anti-C14orf130  antibody (bs-9616R)  
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產品編號 bs-9616R
英文名稱 Rabbit Anti-C14orf130  antibody
中文名稱 14號染色體開放閱讀框130抗體
別    名 Chromosome 14 open reading frame 130; N recognin 7; Putative E3 ubiquitin-protein ligase UBR7; Ubiquitin protein ligase E3 component n-recognin 7 (putative); UBR7; UBR 7; UBR-7; UBR7_HUMAN.  
研究領域 細胞生物  免疫學  鋅指蛋白  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UBR7/C14orf130: 331-425/425 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.

Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

Similarity:
Contains 1 PHD-type zinc finger.
Contains 1 UBR-type zinc finger.

SWISS:
Q8N806

Gene ID:
55148

Database links:

Entrez Gene: 55148 Human

Entrez Gene: 66622 Mouse

Entrez Gene: 314399 Rat

Omim: 613816 Human

SwissProt: Q8N806 Human

SwissProt: Q8BU04 Mouse



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