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Rabbit Anti-FBXL17  antibody (bs-8469R)  
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產品編號 bs-8469R
英文名稱 Rabbit Anti-FBXL17  antibody
中文名稱 FBXL17蛋白抗體
別    名 F box and leucine rich repeat protein 17; F box only protein 13; F box/LRR repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17; FBL17; FBX13; Fbxl17; FBXO13; FBXL13; FXL17_HUMAN; DKFZP434C1715.  
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXL17: 451-550/701 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Interacts with SKP1 and CUL1

Similarity:
Contains 1 F-box domain.

SWISS:
Q9UF56

Gene ID:
64839

Database links:

Entrez Gene: 64839 Human

Entrez Gene: 50758 Mouse

Entrez Gene: 316663 Rat

Omim: 609083 Human

SwissProt: Q9UF56 Human

SwissProt: Q9QZN1 Mouse

Unigene: 657225 Human

Unigene: 721914 Human

Unigene: 136366 Mouse



產品圖片
Sample: MDA-MB-231 cell (Human) Lysate at 30 ug Primary: Anti-FBXL17 (bs-8469R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 76kD Observed band size: 76kD
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