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Rabbit Anti-ZnT-1  antibody (bs-6440R)  
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產(chǎn)品編號 bs-6440R
英文名稱 Rabbit Anti-ZnT-1  antibody
中文名稱 鋅轉(zhuǎn)運蛋白1抗體
別    名 SLC30 A1; SLC30A 1; SLC30A1; Solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 (zinc transporter), member1; Solute carrier family 30 member 1; Solute carrier family 30, member 1; Zinc transporter 1; Zinc transporter1; ZNT 1; ZnT-1; ZNT1_HUMAN; ZRC 1; ZRC1.  
Specific References  (1)     |     bs-6440R has been referenced in 1 publications.
[IF=6.543] Xiao Chuanpi. et al. High Temperature-Induced Oxidative Stress Affects Systemic Zinc Homeostasis in Broilers by Regulating Zinc Transporters and Metallothionein in the Liver and Jejunum. Oxid Med Cell Longev. 2022;2022:1427335  WB ;  Broiler Chicks.  
研究領(lǐng)域 細胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZnT-1: 131-330/507 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.

Function:
May be involved in zinc transport out of the cell.

Subunit:
Multimer.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.

SWISS:
Q9Y6M5

Gene ID:
7779

Database links:

Entrez Gene: 7779 Human

Entrez Gene: 22782 Mouse

Entrez Gene: 58976 Rat

Omim: 609521 Human

SwissProt: Q9Y6M5 Human

SwissProt: Q60738 Mouse

SwissProt: Q62720 Rat

Unigene: 519469 Human

Unigene: 9024 Mouse

Unigene: 10120 Rat



產(chǎn)品圖片
Sample:Large intestine (mouse) Lysate at 40 ug Primary: Anti- ZnT-1(bs-6440R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55kD Observed band size: 55kD
Sample:Lovo cell (human) Lysate at 40 ug Primary: Anti- ZnT-1(bs-6440R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55kD Observed band size: 55kD
Sample: Lane 1: Mouse Small intestine tissue lysates Lane 2: Mouse Heart tissue lysates Lane 3: Rat Small intestine tissue lysates Lane 4: Rat Heart tissue lysates Lane 5: Human HeLa cell lysates Lane 6: Human U251 cell lysates Lane 7: Human K562 cell lysates Lane 8: Human HepG2 cell lysates Primary: Anti-ZnT-1 (bs-6440R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kDa Observed band size: 50 kDa
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