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Rabbit Anti-HOXA9  antibody (bs-6667R)  
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產品編號 bs-6667R
英文名稱 Rabbit Anti-HOXA9  antibody
中文名稱 同源盒蛋白HOXA9抗體
別    名 ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox protein A9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; HXA9_HUMAN.  
Specific References  (1)     |     bs-6667R has been referenced in 1 publications.
[IF=1.39] Ma et al. High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis. (2017) Oncol.Lett. 14:5883-5889  IHC-P ;  Human.  
研究領域 發育生物學  干細胞  轉錄調節因子  內皮細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXA9: 275-272 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
P31269

Gene ID:
3205

Database links:

Entrez Gene: 3205 Human

Entrez Gene: 15405 Mouse

Entrez Gene: 500126 Rat

Omim: 142956 Human

SwissProt: P31269 Human

SwissProt: P09631 Mouse

Unigene: 659350 Human

Unigene: 4694 Mouse

Unigene: 203714 Rat



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