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Rabbit Anti-KIR2DS4/CD158i  antibody (bs-2644R)  
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產品編號 bs-2644R
英文名稱 Rabbit Anti-KIR2DS4/CD158i  antibody
中文名稱 NK細胞抑制性受體2DS4抗體
別    名 Killer cell immunoglobulin-like receptor 2DS4; CD158 antigen like family member I; CD158I; CD158i antigen; CL 17; CL 39; CL17; CL39; Killer cell immunoglobulin like receptor two domains short cytoplasmic tail 4; Killer inhibitory receptor 4 1 2; KIR antigen 2DS4; KIR1D; KIR412; KKA3; MGC120019; MGC125315; MGC125317; MHC class I NK cell receptor; Natural killer associated transcript 8; Natural killer cell inhibitory receptor; NKAT 8; NKAT8; P58 natural killer cell receptor clone CL 39; P58 natural killer cell receptor clone CL39; p58 NK receptor; KI2S4_HUMAN.  
Specific References  (1)     |     bs-2644R has been referenced in 1 publications.
[IF=2.38] Mozer-Lisewska, Iwona, et al. "Detection and Significance of Cytotoxic Cell Subsets in Biopsies of HCV-Infected Human Livers." Archivum immunologiae et therapiae experimentalis (2013): 1-8.  Human.  
研究領域 細胞生物  免疫學  自然殺傷細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD158i: 221-290/290 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells.

Function:
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
P43632

Gene ID:
3809

Database links:

Entrez Gene: 3809 Human

Omim: 604955 Human

SwissProt: P43632 Human

Unigene: 654608 Human



產品圖片
Sample: HL-60 Cell (Human) Lysate at 30 ug Primary: Anti-KIR2DS4'CD158i (bs-2644R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 48 kD
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