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Rabbit Anti-COX7A2  antibody (bs-2562R)  
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產(chǎn)品編號 bs-2562R
英文名稱 Rabbit Anti-COX7A2  antibody
中文名稱 細(xì)胞色素c氧化酶7A2抗體
別    名 Mitochondrion. Cytochrome c oxidase subunit 7A2, mitochondrial; COX7a related protein; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; COX7a-related protein; COX7AR; COX7RP; Cytochrome c oxidase subunit VIIa related protein, mitochondrial; Cytochrome c oxidase subunit VIIaL; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-related protein, mitochondrial [Precursor]; EB1; Estrogen receptor binding CpG island; SIG81; CX7A2_HUMAN.  
研究領(lǐng)域 腫瘤  心血管  信號轉(zhuǎn)導(dǎo)  合成與降解  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 6.7kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COX7A2: 21-83/83 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the cytochrome c oxidase VIIa family.

SWISS:
P14406

Gene ID:
1347

Database links:

Entrez Gene: 1347 Human

Entrez Gene: 12866 Mouse

Entrez Gene: 29507 Rat

Omim: 123996 Human

SwissProt: P14406 Human

SwissProt: P48771 Mouse

SwissProt: P35171 Rat

Unigene: 70312 Human

Unigene: 152627 Mouse

Unigene: 1745 Rat



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with COX7A2 polyclonal antibody, unconjugated (bs-2562R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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