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Rabbit Anti-TNFSF4  antibody (bs-2463R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-2463R
英文名稱 Rabbit Anti-TNFSF4  antibody
中文名稱 腫瘤壞死因子配體超家族成員4抗體
別    名 CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1.  
研究領域 細胞生物  免疫學  細胞表面分子  淋巴細胞  t-淋巴細胞  細胞因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Mouse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TNFSF4: 141-199/199 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Subunit:
Homotrimer (Probable).

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Detected in T-cell lines, but not in a macrophage cell line.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
Q9Z2P3

Gene ID:
89814

Database links:

Entrez Gene: 7292 Human

Entrez Gene: 22164 Mouse

Entrez Gene: 89814 Rat

Omim: 603594 Human

SwissProt: P23510 Human

SwissProt: P43488 Mouse

SwissProt: Q9Z2P3 Rat

Unigene: 181097 Human

Unigene: 4994 Mouse

Unigene: 30043 Rat



產品圖片
Sample: Thymus(Rat) Lysate at 40 ug Primary: Anti- TNFSF4 (bs-2463R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 33 kD
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