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Rabbit Anti-Lxn  antibody (bs-1971R)  
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產品編號 bs-1971R
英文名稱 Rabbit Anti-Lxn  antibody
中文名稱 羧肽酶抑制劑抗體
別    名 ECI; Endogenous carboxypeptidase inhibitor; Latexin protein; MUM; TCI; Tissue carboxypeptidase inhibitor; LXN_HUMAN.  
研究領域 細胞生物  干細胞  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Lxn: 131-222/222 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.

Similarity:
Belongs to the protease inhibitor I47 (latexin) family.

SWISS:
Q9BS40

Gene ID:
56925

Database links:

Entrez Gene: 781644 Cow

Entrez Gene: 56925 Human

Entrez Gene: 17035 Mouse

Entrez Gene: 59073 Rat

Omim: 609305 Human

SwissProt: Q9BS40 Human

SwissProt: P70202 Mouse

SwissProt: Q64361 Rat

Unigene: 478067 Human

Unigene: 2632 Mouse

Unigene: 11404 Rat



Latexin的靶蛋白為羧肽酶,Latexin與炎癥的發展密切相關,主要表達于單核巨噬細胞。
產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with Lxn polyclonal antibody, unconjugated (bs-1971R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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